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Making vessels leaky on demand could aid drug delivery

 

Making vessels leaky on demand could aid drug delivery

Scientists use magnets and nanoparticles to open, close gaps in blood vessel

June 8, 2017 /  Rice University

 

Scientists use magnets and nanoparticles to cause 'leaks' in blood vessels on demand. The technique could help in the delivery of therapeutics to targeted areas in the body, including deep tissues and organs. Rice bioengineer Gang Bao and collaborators at Emory University and the Georgia Institute of Technology reported using magnets to help iron-oxide nanoparticles invade endothelial cells both in the lab and in vivo. Then they use the same magnets to make vessels temporarily "leaky

This permeability would allow large-molecule drugs to reach target tissues, Bao said. Strong magnets may be able to lead nanoparticle-infused stem cells or drug-laden nanoparticles themselves to targeted areas, even in deep tissues like organs that current therapies cannot reach

 

you can read more on link

https://www.sciencedaily.com/releases/2017/06/170608072913.htm